Dr. Ethan Basch is an oncologist and Director of Cancer Outcomes Research at the University of North Carolina. His research group established that up to half of patients’ symptom side effects go undetected during cancer treatment and clinical trials, and that patient engagement and questionnaires substantially improve detection. His team determined that integrating web-based patient-reported symptoms into oncology clinical practice improves clinical outcomes and reduces health service utilization. His team created a system for the National Cancer Institute (NCI) to collect patient-reported side effects during cancer trials called the ‘PRO-CTCAE.’ Dr. Basch is also involved in efforts to bring PROs into comparative effectiveness research, routine care, and quality improvement. He is a member of the Board of Scientific Advisors for the U.S. National Cancer Institute, the Methodology Committee of the Patient-Centered Outcomes Research Institute, and is an Associate Editor at JAMA.